Smith & Nephew Iodoflex Cadexomer Iodine Gel Pad — Kills Bacteria, Debrides
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Smith & Nephew Iodoflex Cadexomer Iodine Gel Pad — Kills Bacteria, Debrides & Absorbs, 2 Sizes
Three clinical actions. One dressing. Built-in color change tells you when to change it. Smith & Nephew Iodoflex is a sterile cadexomer iodine gel pad dressing that simultaneously debrides slough and soft necrotic tissue, delivers broad-spectrum antimicrobial activity through the sustained release of 0.9% iodine for up to 72 hours, and absorbs exudate, pus, and debris — forming a gel over the wound surface that maintains a moist healing environment throughout wear. Each gram of Iodoflex absorbs approximately 3ml of fluid, and the pad absorbs up to 6 times its own weight in total — dramatically reducing dressing change frequency for heavily exuding infected wounds. As the cadexomer beads absorb fluid and release iodine, the pad changes color from brown to yellow-gray — a clear, visible signal that tells clinicians and caregivers exactly when the dressing needs to be changed, eliminating guesswork entirely.
✔ 0.9% Cadexomer Iodine — Broad-Spectrum Antimicrobial Activity Up to 72 Hours ✔ Kills MRSA & Pseudomonas — Clinically Proven ✔ Debrides Slough & Soft Necrotic Tissue — Unique Cadexomer Matrix ✔ Absorbs Up to 6x Its Weight — Fewer Dressing Changes ✔ Color Change Indicator — Brown to Yellow-Gray Signals Time to Change
Product Details
| Manufacturer | Smith & Nephew |
|---|---|
| Product | Iodoflex Cadexomer Iodine Gel Pad Dressing |
| Available Sizes | 2 sizes — Item #s 6602133005 and 6602134010 (see size guide below) |
| Active Ingredient | 0.9% Cadexomer Iodine — sustained release up to 72 hours |
| Absorbency | Each gram absorbs approximately 3ml of fluid — up to 6x the pad's own weight total |
| Change Indicator | Color change from brown to yellow-gray signals dressing change needed |
| Change Frequency | Typically 2 to 3 times per week — guided by color change indicator |
| Adherence | Non-adherent — reduces trauma at dressing changes, encourages patient compliance |
| Secondary Dressing | Required — cover with an appropriate absorbent secondary dressing |
| Compression Compatible | Yes — can be used under compression therapy |
| Biodegradable | Yes |
| Sterility | Sterile |
| Latex | Not made with natural rubber latex |
Indicated For — Wound Types
- Infected venous stasis ulcers and leg ulcers — including wounds under compression therapy
- Infected pressure ulcers and pressure injuries
- Infected diabetic foot ulcers
- Infected traumatic wounds
- Infected surgical wounds
- Chronic exuding wounds with slough, soft necrotic tissue, or debris requiring debridement
- Wounds with suspected or confirmed MRSA or Pseudomonas aeruginosa infection
- Wet ulcers and wounds requiring simultaneous antimicrobial action and exudate control
Important Contraindications: Do not use on dry necrotic tissue. Not for use in patients with known or suspected iodine sensitivity, Hashimoto's Thyroiditis, Grave's Disease, or non-toxic nodular goiter. Not for use by pregnant or lactating women. Not for use in children 14 years and under. Use with caution in patients with severely impaired renal function or any history of thyroid disorder. Potential interaction with lithium — increased risk of hypothyroidism. Do not use concomitantly with mercurial antiseptics or taurolidine.
How Iodoflex Works — What Makes It Different
Most antimicrobial dressings deliver a single mechanism — silver dressings kill bacteria but don't debride, hydrogels debride but don't address infection, standard foam dressings absorb but have no antimicrobial activity. Iodoflex delivers all three in a single application through its unique cadexomer matrix technology. The cadexomer beads that make up the pad are engineered to do three things simultaneously as they absorb wound fluid: physically remove slough, soft necrotic tissue, and debris from the wound bed through the absorptive action of the matrix; release iodine in a sustained, controlled manner as the beads swell — providing up to 72 hours of broad-spectrum bactericidal activity without the cytotoxic spike of free iodine solutions; and form a gel over the wound surface that maintains the moist environment necessary for granulation and re-epithelialization. In clinical testing Iodoflex has demonstrated bactericidal activity against 103 isolates of MRSA and 101 strains of Pseudomonas aeruginosa — two of the most treatment-resistant organisms in chronic wound management.
- Cadexomer matrix physically removes slough, soft necrotic tissue, and debris — active wound bed preparation with every application
- 0.9% iodine released in a sustained, controlled manner — broad-spectrum bactericidal activity up to 72 hours per application
- Bactericidal against MRSA (103 isolates tested) and Pseudomonas aeruginosa (101 strains tested) in vitro
- Gel formation over wound surface — maintains moist wound healing environment throughout wear
- Absorbs up to 6x its weight in fluid — each gram handles approximately 3ml of exudate
- Color change from brown to yellow-gray — unambiguous, visible signal that iodine is exhausted and dressing change is due
- Non-adherent — lifts away from healing tissue without trauma, supporting patient compliance
- Pliable and conformable — shapes to fit irregular wound contours without cutting
- Reduces wound odor — clinically noted improvement in odor management for infected wounds
- Compatible with compression therapy — suitable for venous ulcer management under compression wraps
- Biodegradable formulation
The Cadexomer Matrix — Three-in-One Wound Bed Preparation
Standard iodine solutions deliver iodine at a high initial concentration that drops rapidly and can be cytotoxic to healing tissue. The cadexomer matrix in Iodoflex solves this by binding iodine within the bead structure and releasing it only as the beads absorb fluid — delivering a low, sustained concentration that is bactericidal without being cytotoxic. This sustained-release mechanism is what allows Iodoflex to remain clinically effective for up to 72 hours per application rather than requiring daily changes typical of solution-based antimicrobials.
| Action | How It Works |
|---|---|
| Debridement | Cadexomer beads absorb and physically lift slough, soft necrotic tissue, and debris from the wound bed as they swell |
| Antimicrobial | 0.9% iodine released in sustained, controlled low doses as beads absorb — bactericidal for up to 72 hours without cytotoxic iodine spike |
| Exudate Control | High-absorbency matrix locks exudate away from the wound surface — gel formation maintains the moist environment needed for healing |
Choosing the Right Size
- 6602133005 — 5g Pad, 1½" x 2⅜" — Box of 5 — Smaller size — ideal for compact infected wounds, small venous ulcers, pressure injuries, and wounds where precise pad placement in a limited area is needed
- 6602134010 — 10g Pad, 2⅛" x 3" — Box of 3 — Larger size — the standard choice for medium-to-large infected wounds, deeper ulcers with significant slough burden, and wounds with higher exudate output requiring greater absorbent capacity per application
Application Tip: Select the size that covers the wound surface completely. The pad should contact the entire wound bed. Cover with an appropriate absorbent secondary dressing. Remove by moistening with saline if adhering. Rinse remaining Iodoflex from the wound with a gentle stream of saline or sterile water before reapplying.
Not sure which size is right for your wound? Call 1-866-218-0902 — Mon–Fri, 9am–5pm EST
Why Buy From Medical Department Store?
- 30+ years serving home medical, wound care, and clinical supply customers
- 110% Low Price Guarantee — we beat any competitor's price
- Medical supply specialists on the phone — not a call center
- Ships to all 50 states — 5 Southwest Florida locations for local pickup
- Full-service medical supply store — Home Medical Equipment, Mobility, Respiratory & Beds
Questions about Iodoflex or any of our antimicrobial wound dressings? Call 1-866-218-0902 — our team is ready to help.
