{"product_id":"3m-promogran-matrix","title":"PROMOGRAN Matrix Wound Dressing","description":"\u003cdiv style=\"font-family: Arial, sans-serif; max-width: 800px; margin: 0 auto; color: #333;\"\u003e\n\n  \u003ch1 style=\"background-color: #cc0000; color: #fff; padding: 15px; text-align: center; font-size: 20px;\"\u003e\n    3M Promogran Matrix — ORC + Collagen, No Silver, 3.4x More Wound Closures, 2 Sizes\n  \u003c\/h1\u003e\n\n  \u003cp style=\"font-size: 15px; line-height: 1.6;\"\u003e\n    \u003cstrong\u003eThe original ORC + collagen wound dressing — clinically proven to give stalled chronic wounds 3.4 times greater odds of closure, without silver.\u003c\/strong\u003e 3M Promogran Matrix is a sterile freeze-dried composite of 55% collagen and 45% Oxidized Regenerated Cellulose (ORC) — the original formulation of the Promogran Matrix Family and the only collagen dressing of its kind for patients where silver is contraindicated or not clinically indicated. Like Promogran Prisma, Promogran Matrix transforms on contact with wound exudate into a soft, conformable, biodegradable gel that covers the entire wound surface — absorbing and inactivating the matrix metalloproteinases (MMPs) and elastases that chronically stall wound healing, providing native collagen scaffolding for fibroblast migration and granulation tissue formation, and maintaining the physiologically moist microenvironment essential for epithelialization. The biodegradable gel absorbs progressively into the wound over time — no removal required at dressing changes. Backed by the same meta-analysis of 10 randomized controlled trials demonstrating 3.4 times greater odds of wound closure compared to standard dressings.\n  \u003c\/p\u003e\n\n  \u003cp style=\"font-size: 15px; line-height: 1.6;\"\u003e\n    ✔ Only ORC + Collagen Dressing Without Silver — Ideal for Silver-Sensitive Patients    ✔ 3.4x Greater Odds of Wound Closure — Same RCT Evidence Base as Promogran Prisma    ✔ ORC Inactivates MMPs — Removes the Biochemical Barrier Stalling Chronic Wounds    ✔ Biodegradable Gel — No Removal Required at Dressing Changes    ✔ Compression \u0026amp; NPWT Compatible — Versatile Across Wound Protocols\n  \u003c\/p\u003e\n\n  \u003chr\u003e\n\n  \u003ch2 style=\"background-color: #f5f5f5; padding: 10px; border-left: 4px solid #cc0000;\"\u003eProduct Details\u003c\/h2\u003e\n  \u003ctable style=\"width: 100%; border-collapse: collapse; margin-bottom: 20px;\"\u003e\n    \u003ctr style=\"background-color: #f9f9f9;\"\u003e\n      \u003cth style=\"padding: 8px; border: 1px solid #ddd; width: 40%; text-align: left;\"\u003eManufacturer\u003c\/th\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eSolventum (Formerly 3M \/ Systagenix \/ KCI)\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr\u003e\n      \u003cth style=\"padding: 8px; border: 1px solid #ddd; text-align: left;\"\u003eProduct\u003c\/th\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003ePromogran Matrix — Collagen\/ORC Wound Dressing (Silver-Free)\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background-color: #f9f9f9;\"\u003e\n      \u003cth style=\"padding: 8px; border: 1px solid #ddd; text-align: left;\"\u003eAvailable Sizes\u003c\/th\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003e2 sizes — MA022 (4.34 sq in) and MA033 (19.1 sq in) — see size guide below\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr\u003e\n      \u003cth style=\"padding: 8px; border: 1px solid #ddd; text-align: left;\"\u003eComposition\u003c\/th\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003e55% Collagen and 45% Oxidized Regenerated Cellulose (ORC) — sterile freeze-dried composite, no silver\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background-color: #f9f9f9;\"\u003e\n      \u003cth style=\"padding: 8px; border: 1px solid #ddd; text-align: left;\"\u003eORC Technology\u003c\/th\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eOnly collagen dressing with ORC — absorbs and inactivates MMPs and elastases that chronically stall wound healing\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr\u003e\n      \u003cth style=\"padding: 8px; border: 1px solid #ddd; text-align: left;\"\u003eSilver Content\u003c\/th\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eNone — silver-free formulation for patients with silver sensitivity or where silver is not indicated\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background-color: #f9f9f9;\"\u003e\n      \u003cth style=\"padding: 8px; border: 1px solid #ddd; text-align: left;\"\u003eClinical Evidence\u003c\/th\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eMeta-analysis of 10 RCTs — 3.4x greater odds of wound closure vs standard dressings (OR=3.4, 95% CI [1.15, 10.1], p=0.027)\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr\u003e\n      \u003cth style=\"padding: 8px; border: 1px solid #ddd; text-align: left;\"\u003eGel Formation\u003c\/th\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eTransforms into soft conformable biodegradable gel on contact with exudate — covers all wound areas including contours\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background-color: #f9f9f9;\"\u003e\n      \u003cth style=\"padding: 8px; border: 1px solid #ddd; text-align: left;\"\u003eBiodegradable\u003c\/th\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eYes — gel absorbs progressively into the wound, no removal required at dressing changes\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr\u003e\n      \u003cth style=\"padding: 8px; border: 1px solid #ddd; text-align: left;\"\u003eChange Frequency\u003c\/th\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eEvery 72 hours or as directed — residual dressing does not need to be removed at change\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background-color: #f9f9f9;\"\u003e\n      \u003cth style=\"padding: 8px; border: 1px solid #ddd; text-align: left;\"\u003eCompression Compatible\u003c\/th\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eYes — suitable for use under compression bandaging\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr\u003e\n      \u003cth style=\"padding: 8px; border: 1px solid #ddd; text-align: left;\"\u003eNPWT Compatible\u003c\/th\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eYes — compatible with 3M ActiV.A.C. Therapy System under medical supervision\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background-color: #f9f9f9;\"\u003e\n      \u003cth style=\"padding: 8px; border: 1px solid #ddd; text-align: left;\"\u003eMRI Safety\u003c\/th\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eMRI Safe — no silver component, no MRI restriction\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr\u003e\n      \u003cth style=\"padding: 8px; border: 1px solid #ddd; text-align: left;\"\u003eSecondary Dressing\u003c\/th\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eRequired — semi-occlusive or non-occlusive secondary dressing to maintain moist environment\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background-color: #f9f9f9;\"\u003e\n      \u003cth style=\"padding: 8px; border: 1px solid #ddd; text-align: left;\"\u003eSterility\u003c\/th\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eSterile — 10 per box (MA022) | 10 per box (MA033)\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr\u003e\n      \u003cth style=\"padding: 8px; border: 1px solid #ddd; text-align: left;\"\u003eHCPCS Codes\u003c\/th\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eA6021 (MA022 — 4.34 sq in) | A6022 (MA033 — 19.1 sq in)\u003c\/td\u003e\n    \u003c\/tr\u003e\n  \u003c\/table\u003e\n\n  \u003chr\u003e\n\n  \u003ch2 style=\"background-color: #f5f5f5; padding: 10px; border-left: 4px solid #cc0000;\"\u003eIndicated For — Wound Types\u003c\/h2\u003e\n  \u003cul style=\"font-size: 15px; line-height: 1.8;\"\u003e\n    \u003cli\u003eDiabetic foot ulcers — stalled or chronic, particularly where silver is not indicated\u003c\/li\u003e\n    \u003cli\u003eVenous leg ulcers — with or without compression\u003c\/li\u003e\n    \u003cli\u003ePressure injuries and ulcers — all stages\u003c\/li\u003e\n    \u003cli\u003eUlcers caused by mixed vascular etiologies\u003c\/li\u003e\n    \u003cli\u003eTraumatic wounds — abrasions, lacerations, donor sites, and bleeding surface wounds\u003c\/li\u003e\n    \u003cli\u003eSurgical wounds healing by secondary intention\u003c\/li\u003e\n    \u003cli\u003eFull and partial thickness wounds with exudate\u003c\/li\u003e\n    \u003cli\u003eWounds stalled in the inflammatory phase where silver is contraindicated or not clinically needed\u003c\/li\u003e\n    \u003cli\u003ePatients with known silver sensitivity — silver-free alternative to Promogran Prisma\u003c\/li\u003e\n    \u003cli\u003eWounds requiring MRI-compatible wound management — no silver means no MRI restriction\u003c\/li\u003e\n  \u003c\/ul\u003e\n  \u003cp style=\"font-size: 15px; line-height: 1.6;\"\u003e\u003cstrong\u003eContraindications:\u003c\/strong\u003e Not indicated for wounds with active vasculitis, third-degree burns, or patients with known sensitivity to ORC or collagen. May be used on infected wounds only when proper medical treatment addresses the underlying infection. Not a substitute for infection treatment.\u003c\/p\u003e\n\n  \u003chr\u003e\n\n  \u003ch2 style=\"background-color: #f5f5f5; padding: 10px; border-left: 4px solid #cc0000;\"\u003eHow It Works — ORC + Collagen Without Silver\u003c\/h2\u003e\n\n  \u003cp style=\"font-size: 15px; line-height: 1.6;\"\u003e\n    Promogran Matrix works through exactly the same ORC + collagen mechanism as Promogran Prisma — the silver-free formulation delivers identical wound healing performance for wounds that do not require active antimicrobial coverage. The ORC component absorbs and inactivates MMPs and elastases from wound fluid, removing the biochemical stall mechanism that prevents chronic wounds from progressing. With destructive proteases neutralized, the collagen scaffold can function as intended — providing the structural framework for fibroblast migration, granulation tissue formation, and re-epithelialization across the wound bed. The dressing transforms on contact with exudate into a soft biodegradable gel that adapts to the wound surface, maintains the physiologically moist environment, and absorbs progressively into the wound between dressing changes. The clinical outcome is equivalent to Promogran Prisma for wounds without active infection — making Promogran Matrix the right choice when silver is not indicated, contraindicated, or when MRI compatibility is a requirement.\n  \u003c\/p\u003e\n\n  \u003cul style=\"font-size: 15px; line-height: 1.8;\"\u003e\n    \u003cli\u003eORC absorbs and inactivates MMPs and elastases — removes biochemical barrier stalling chronic wound healing\u003c\/li\u003e\n    \u003cli\u003eOnly collagen dressing with ORC — unique mechanism not available in standard collagen dressings\u003c\/li\u003e\n    \u003cli\u003eCollagen scaffold supports fibroblast migration, granulation tissue formation, and epithelialization\u003c\/li\u003e\n    \u003cli\u003eTransforms into biodegradable conformable gel — covers all wound contours, no gaps\u003c\/li\u003e\n    \u003cli\u003eGel absorbs into wound over time — no removal required at dressing changes\u003c\/li\u003e\n    \u003cli\u003eMaintains physiologically moist microenvironment throughout wear\u003c\/li\u003e\n    \u003cli\u003eProven in meta-analysis of 10 RCTs — 3.4x greater odds of wound closure vs standard dressings\u003c\/li\u003e\n    \u003cli\u003eSilver-free — appropriate for silver-sensitive patients and silver-contraindicated wound protocols\u003c\/li\u003e\n    \u003cli\u003eMRI safe — no silver means no imaging restrictions during wound management\u003c\/li\u003e\n    \u003cli\u003eCompression and NPWT compatible — same versatility as Promogran Prisma\u003c\/li\u003e\n  \u003c\/ul\u003e\n\n  \u003chr\u003e\n\n  \u003ch2 style=\"background-color: #f5f5f5; padding: 10px; border-left: 4px solid #cc0000;\"\u003ePromogran Matrix vs. Promogran Prisma — Choosing the Right Version\u003c\/h2\u003e\n\n  \u003ctable style=\"width: 100%; border-collapse: collapse; margin-bottom: 20px;\"\u003e\n    \u003ctr style=\"background-color: #cc0000; color: #fff;\"\u003e\n      \u003cth style=\"padding: 8px; border: 1px solid #ddd; text-align: left; width: 40%;\"\u003eChoose Promogran Matrix (MA022\/MA033) When:\u003c\/th\u003e\n      \u003cth style=\"padding: 8px; border: 1px solid #ddd; text-align: left;\"\u003eChoose Promogran Prisma (MA028\/MA019) When:\u003c\/th\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background-color: #f9f9f9;\"\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eWound is clean, non-infected, and healing is stalled without active infection\u003c\/td\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eWound is infected, colonized, or at high risk of bacterial complications\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003ePatient has known silver sensitivity or silver is contraindicated\u003c\/td\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eAntimicrobial protection is clinically indicated alongside ORC\/collagen therapy\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background-color: #f9f9f9;\"\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eMRI imaging is required or anticipated during wound management\u003c\/td\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eMRI is not anticipated and silver's antibacterial barrier is beneficial\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eClinical protocol calls for silver-free wound management\u003c\/td\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eWound has MRSA, Pseudomonas, or other resistant organism colonization\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background-color: #f9f9f9;\"\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eORC + collagen wound healing benefit is the primary goal without antimicrobial need\u003c\/td\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eBoth wound healing acceleration and infection protection are simultaneously needed\u003c\/td\u003e\n    \u003c\/tr\u003e\n  \u003c\/table\u003e\n\n  \u003chr\u003e\n\n  \u003ch2 style=\"background-color: #f5f5f5; padding: 10px; border-left: 4px solid #cc0000;\"\u003eHow to Apply — Step by Step\u003c\/h2\u003e\n  \u003ctable style=\"width: 100%; border-collapse: collapse; margin-bottom: 20px;\"\u003e\n    \u003ctr style=\"background-color: #cc0000; color: #fff;\"\u003e\n      \u003cth style=\"padding: 8px; border: 1px solid #ddd; text-align: left; width: 10%;\"\u003eStep\u003c\/th\u003e\n      \u003cth style=\"padding: 8px; border: 1px solid #ddd; text-align: left;\"\u003eAction\u003c\/th\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background-color: #f9f9f9;\"\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003e\u003cstrong\u003e1\u003c\/strong\u003e\u003c\/td\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003ePrepare wound bed per standard protocol — debride necrotic tissue before applying\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003e\u003cstrong\u003e2\u003c\/strong\u003e\u003c\/td\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eCut to fit the wound with scissors if needed — cover the entire wound bed surface\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background-color: #f9f9f9;\"\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003e\u003cstrong\u003e3\u003c\/strong\u003e\u003c\/td\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eIf wound has exudate — apply directly, exudate will initiate gel transformation\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003e\u003cstrong\u003e4\u003c\/strong\u003e\u003c\/td\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eIf wound is dry — moisten with sterile saline or Ringer's solution before or after application to initiate gel formation\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background-color: #f9f9f9;\"\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003e\u003cstrong\u003e5\u003c\/strong\u003e\u003c\/td\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eCover with a semi-occlusive or non-occlusive secondary dressing fixed with non-irritating tape — compression bandage if indicated\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003e\u003cstrong\u003e6\u003c\/strong\u003e\u003c\/td\u003e\n      \u003ctd style=\"padding: 8px; border: 1px solid #ddd;\"\u003eAt dressing change — residual gel does not need to be removed, apply fresh Promogran Matrix every 72 hours\u003c\/td\u003e\n    \u003c\/tr\u003e\n  \u003c\/table\u003e\n\n  \u003chr\u003e\n\n  \u003ch2 style=\"background-color: #f5f5f5; padding: 10px; border-left: 4px solid #cc0000;\"\u003eChoosing the Right Size\u003c\/h2\u003e\n  \u003cul style=\"font-size: 15px; line-height: 1.8;\"\u003e\n    \u003cli\u003e\n\u003cstrong\u003eMA022 — 4.34 sq in (approx. 2¼\" x 2¼\" hexagon) — 10\/box\u003c\/strong\u003e — Standard size — the most widely used size for general diabetic ulcer, venous ulcer, and pressure injury management. The hexagon shape provides better wound edge coverage than a standard square. Best for wounds up to approximately 4 square inches in surface area.\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eMA033 — 19.1 sq in (approx. 4¾\" x 4¾\") — 10\/box\u003c\/strong\u003e — Large size — for broader wounds, large pressure injuries, extensive post-surgical sites, and any wound that exceeds the MA022 coverage area. Can be cut to shape. More cost-effective per square inch for large wound applications.\u003c\/li\u003e\n  \u003c\/ul\u003e\n  \u003cp style=\"font-size: 15px; line-height: 1.6;\"\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e Store below 25°C (77°F) away from direct light to maintain product integrity.\u003c\/p\u003e\n  \u003cp style=\"font-size: 15px; line-height: 1.6;\"\u003eNot sure which size or which Promogran version is right for your wound? \u003cstrong\u003e\u003ca href=\"tel:18662180902\"\u003eCall 1-866-218-0902\u003c\/a\u003e\u003c\/strong\u003e — Mon–Fri, 9am–5pm EST\u003c\/p\u003e\n\n  \u003chr\u003e\n\n  \u003ch2 style=\"background-color: #f5f5f5; padding: 10px; border-left: 4px solid #cc0000;\"\u003eWhy Buy From Medical Department Store?\u003c\/h2\u003e\n  \u003cul style=\"font-size: 15px; line-height: 1.8;\"\u003e\n    \u003cli\u003e30+ years serving home medical, wound care, and clinical supply customers\u003c\/li\u003e\n    \u003cli\u003e110% Low Price Guarantee — we beat any competitor's price\u003c\/li\u003e\n    \u003cli\u003eMedical supply specialists on the phone — not a call center\u003c\/li\u003e\n    \u003cli\u003eShips to all 50 states — 5 Southwest Florida locations for local pickup\u003c\/li\u003e\n    \u003cli\u003eFull-service medical supply store — Home Medical Equipment, Mobility, Respiratory \u0026amp; Beds\u003c\/li\u003e\n  \u003c\/ul\u003e\n  \u003cp style=\"font-size: 15px; line-height: 1.6;\"\u003eQuestions about Promogran Matrix or Promogran Prisma? \u003cstrong\u003e\u003ca href=\"tel:18662180902\"\u003eCall 1-866-218-0902\u003c\/a\u003e\u003c\/strong\u003e — our team is ready to help you choose the right version.\u003c\/p\u003e\n\n\u003c\/div\u003e","brand":"Solventum (Formerly 3M)","offers":[{"title":"Default Title","offer_id":55234670428529,"sku":"PG019","price":16.98,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0919\/6122\/9681\/files\/3m_PG004-bx-ea-1.avif?v=1778088192","url":"https:\/\/www.medicaldepartmentstore.com\/products\/3m-promogran-matrix","provider":"Medical Department Store","version":"1.0","type":"link"}