Portable Concentrators

Breathing Easy Is Not a Luxury. It’s Your Life 

If you or someone you love relies on supplemental oxygen, choosing the right portable oxygen concentrators for sale can make a world of difference. It's the difference between being home and getting to your granddaughter's recital. Between themorning walk on the beach and sitting outside

Medical Department Store ships to all 50 states and delivers to the communities of Southwest Florida from Venice to Naples. Our team is comprised of licensed Respiratory Therapists (not sales persons) who examine your prescription, ensure that the unit you are interested in fulfills your clinical needs and ensure you never leave with the wrong equipment. 

Whether you need a featherlight lightweight oxygen concentrator to get you through your daily errands, or a powerful continuous portable oxygen concentrator to last through the night, we have the whole range – and we’ll make sure you leave with the correct fit.

📞 Call 866-218-0902 to speak with a licensed Respiratory Therapist today — or walk into any of our five Southwest Florida locations. No appointment needed.

What Is a Portable Oxygen Concentrator and How Does It Work?

A portable oxygen concentrator takes the air in the environment around you, removes the nitrogen, and provides the purified oxygen through a nasal cannula. No tanks. No refills. No worry about running out mid-walk. 

The best portable oxygen concentratorsfor sale are more than simply a medical equipment for those managing COPD, pulmonary fibrosis or other disorders needing supplemental oxygen; they are freedom. It means saying yes when your children invite you to dinner. It means getting on a plane without fear. It is to live life the way you want. 

There are two basic delivery types and the wrong one is the single most often – and costly – mistake we see. Here’s what you should know.Read ourPortable Oxygen Concentrator Buyer's Guide to understand which type matches your prescription before you shop.

Pulse Dose vs. Continuous Flow: Which Type Do You Need?

Pulse Dose Portable Oxygen Concentrators

Pulse dosage units detect the precise moment you begin to breathe in and give you an accurate puff of oxygen timed with your breath. They're lighter, last longer on a single battery charge, and give you nothing between breaths. This makes them excellent for active daytime use, and travel. Most of the lightweight oxygen concentrators in this category are as little as 2.8 lbs. 

Best for: Everyday wear, travel, active patients, and those that put weight and battery life first. 

Important: Physician assistance is essential for pulse dosage during sleep.

Continuous Flow Portable Oxygen Concentrators

A continuous portable oxygen concentrator delivers a steady, uninterrupted stream of oxygen at a set liters-per-minute (LPM) rate — the same way home concentrators and oxygen tanks work. These units are heavier than pulse dose models, but they are essential for patients whose prescription specifies an LPM delivery rate, overnight or sleep use, or CPAP/BiPAP compatibility.

Best for: Sleep use, higher oxygen requirements, complex prescriptions, CPAP/BiPAP users.

Not sure which type your prescription calls for? Our Respiratory Therapists can answer that in a single phone call. 📞  866-218-0902  |✉  support@medicaldepartmentstore.com

Compare: Pulse Dose vs. Continuous Flow at a Glance

Feature Pulse Dose Continuous Flow
How oxygen is delivered On each inhale (breath-triggered) Constant stream at set LPM
Weight range 2.8 – 6 lbs 16 – 20 lbs
Battery life Longer (up to 13 hrs) Shorter (up to 5 hrs)
FAA Approved Oxygen Concentrator ✅ Yes ✅ Yes
Approved for sleep use Consult MD ✅ Yes
Works with CPAP/BiPAP ❌ No ✅ Yes
Can replace home concentrator Typically no ✅ Yes (dual-mode units)
Best for Active daytime use, travel Overnight, complex prescriptions

Compare Popular Portable Oxygen Concentrators for Sale: Model by Model

Every unit below is available for hands-on demonstration at our five Southwest Florida showrooms.

Model Type Weight Battery* FAA Approved Sleep Use Best For
Inogen One G4 Pulse Dose 2.8 lbs Up to 5 hrs ✅ Yes Consult MD Lightest option, short outings
Inogen One G5 Pulse Dose 4.7 lbs Up to 13 hrs ✅ Yes Consult MD All-day active use, travel
OxyGo NEXT Pulse Dose 4.7 lbs Up to 13 hrs ✅ Yes Consult MD Extended daily outings
Rove 6 Pulse Dose 4.9 lbs Up to 10 hrs ✅ Yes Consult MD Versatile everyday use
3B Aer X Pulse Dose 5.5 lbs Up to 9 hrs ✅ Yes Consult MD Budget-friendly travel
CAIRE Eclipse 5 Dual Mode 18.4 lbs Up to 5 hrs ✅ Yes ✅ Yes 24/7 use, home replacement
OxLife Independence Continuous 19.8 lbs Up to 4 hrs ✅ Yes ✅ Yes Full home replacement, CPAP
OxLife Liberty 2 Continuous 16.5 lbs Up to 4 hrs ✅ Yes ✅ Yes High-flow requirements

5 Things That Actually Determine the Best Portable Oxygen Concentrator for You

There is no single 'best' unit, only the best unit for your situation. It’s what our Respiratory Therapists work through with every patient. 

1. Prescription - pulse setting or flow rate in LPM. 

Here’s the non-negotiable baseline. And that’s where everything else comes from. Bring your prescription when you visit any of our five Southwest Florida locations. If you don’t have it yet, call us and we’ll let you know what to ask your doctor. 

2. The weight you can handle each day. Not just once. 

On a tough day, the difference between a 6.3-lb unit and a 4.7-lb unit is real by mid-afternoon. It’s better to have a lightweight oxygen concentrator that you’ll use, than a heavier one that you leave at home. Be honest about your actual ability, not your best day. 

3. Designed for Florida heat, battery longevity. 

Manufacturer standards are tested in ideal conditions. In Southwest Florida summers use 70-75% of the claimed battery life. Stop by and let’s figure out real-world battery hours for your unique schedule and environment. 

4. Your travel plans. 

Flying domestically? All units we sell are FAA approved oxygen concentrators. International travel adds voltage compatibility and airline-specific paperwork. Cruising out of Fort Myers or Tampa? Call us before you book and we’ll run you through exactly what you’ll need at the gate and on board. 

5. Hurricane season is a planning requirement, not an afterthought. 

If you rely on powered medical equipment, you need a storm plan before a storm is called. That includes knowing your battery hours, your DC auto powers alternatives and your generator compatibility. Come in to any of our Southwest Florida locations in April or May and we will put together a real emergency plan for your individual unit and scenario. This is our one of our most essential conversations with our community.

Why Southwest Florida Trusts Medical Department Store for Portable Oxygen Concentrators for Sale

On Staff Licensed Respiratory Therapists 

Not salespeople with a product card – licensed clinical personnel who can read your prescription, confirm the unit is delivering what your physician intended at your unique setting, and highlight mismatches before they cost you weeks of poor quality of life. That kind of clinical review doesn’t happen online.

10 Day Risk Free Trial 

Bring home any unit. Use it for 10 full days on your actual schedule — errands, grandkids, beach walks, everything. If it’s wrong for your real life, send it back and swap it. No restocking fee, no fine print, no waiting for a return packageNo internet merchant can provide you with this. 

Managed Direct Medicare Billing 

We look over your coverage before you decide anything and tell you honestly what will qualify and what won’t. Bring your Medicare card and prescription when you come in, we’ll do the rest. 

Service for All Brands and Models 

All five Southwest Florida facilities service and repair all portable oxygen concentrators, no matter where you purchased yours. We can come to you if you are unable to come to our office. 

Shipping & Expert Help, Nationwide 

Not in Southwest Florida? We supply portable oxygen concentrators for sale to all 50 states, with the same expert pre- and post-purchase service by phone and emailYou are never left alone after you buy.

Flying with an FAA Approved Oxygen Concentrator — What You Need to Know

All our units are FAA approved oxygen concentrators for use on domestic commercial flights. But FAA permission is just the beginning. Physician certification, battery life calculations, advance reporting to the airline, and airline-specific norms are among the additional oxygen requirements. International travel requires consideration of voltage compatibility.

⚠️  Planning a Flight?

Before your first flight with a new unit, call us. We’ll make sure you have everything you need before you get to the gate. 📞  866-218-0902

Quick Travel Checklist for POC Users

  • Ensure your unit is an FAA approved oxygen concentrator (all of our models are) 

  • Inform your airline when you book – most require 48 hours’ notice 

  • Carry your doctor’s letter and oxygen prescription with you 

  • Calculate battery hours: Flight time + boarding time + delays + 3 hour buffer 

  • When traveling internationally, check the voltage and check the guidelines for that country/carrier. 

  • Cruising from Fort Myers or Tampa? Call us first - cruise liners have their own rules about medical equipment

Tips to Keep Your Lightweight Oxygen Concentrator Running Its Best

Your concentrator is a medical instrument of perfection. A few basic behaviors will make it last longer and keep you safe from unexpected failures – a particularly vital consideration in Southwest Florida, where heat and coastal humidity stress both filters and electronics more than in inland areas. 

Each Week 

Wipe off the outside and examine your nasal cannula for wear. Change the cannula every 2–4 weeks. 

Per month 

Take out your external particle filter and flush it out, air dry well. Inland settings collect garbage slower than Coastal Southwest Florida. Don’t put a wet filter back in. 

Warning Signs to Watch Out for in Progress 

Signs of sieve bed breakdown include increased dyspnea and drifting pulse-ox readings – the most common reason a unit is delivering less oxygen than required even if it appears to beoperating normally. If anything feels odd, bring your unit in for a clinical output check. We test all brands at all five locations.

Frequently Asked Questions 

Can I go to a portable concentrator and no longer use my home tanks? 

Yes, for the appropriate patients and the proper units. For instance, continuous portable oxygen concentratorswith dual-mode like the OxLife Independence and CAIRE Eclipse 5 are made for continuous use including sleeping. Pulse dosage units usually are designed to be used just while you are awake, depending on your prescription and breathing pattern. Whether it makes sense to remove your home equipment in a single phone call or visit can be determined by our Respiratory Therapists based on your specific scenario. 

Are portable oxygen concentrators for sale covered by Medicare? 

Portable oxygen equipment may be covered under Medicare Part B with qualifying diagnosis and physician verification. We handle your Medicare billing, just give us a call before your appointment and we will check your coverage first so you know precisely what to expect before you make any decisions. 

📞 866-218-0902 | ✉ support@medicaldepartmentstore.com

Are portable oxygen concentrators approved for plane travel? 

All units we stock are FAA approved oxygen concentrators that are cleared for domestic commercial flights. Supplemental oxygen to be used on the flight must be approved by a physician, meet battery hour requirements, and be pre-notified to the airline, usually 48 hours in advance. International routes include voltage and carrier specific restrictions. Give us a call before you take your first flight on a new unit and we’ll walk you through it all. 

Do you service concentrators that you didn't sell? 

Yes. Every brand. Every model. No matter where you bought it. We service all portable oxygen concentrators at all 5 locations in Southwest Florida: Venice, Sarasota, Port Charlotte, Fort Myers and Naples. We also provide home service calls to patients who are unable to see us. 

Can I take a unit home to try it out before I buy? 

Sure. Our 10-Day No Risk Trial is exactly what it sounds like. Take any concentrator home, use it for 10 days on your actual daily schedule, and exchange it if it’s not right — no restocking fee, no fine print, no penalty. All five locations accept walk-ins, or call ahead for home delivery.

Five Southwest Florida Locations — Walk In Anytime

Respiratory Therapists on staff  ·  Hands-on demonstrations  ·  10-Day Trial  ·  Medicare billing  ·  Repairs for all brands

Location Address Phone
Venice 1180 Jacaranda Blvd 941-497-2273
Sarasota 3672 Webber St 941-923-7556
Port Charlotte 4265 Tamiami Trail 941-743-6644
Fort Myers 8595 College Pkwy 239-482-6111
Naples 13030 Livingston Rd 239-529-2242

📞  866-218-0902  |  ✉  support@medicaldepartmentstore.com

Monday–Friday 9AM–5PM  |  Saturday 9AM–3PM  |  Nationwide shipping available

Related Resources

  • 2026 Portable Oxygen Concentrator Buyer’s Guide → Every model compared side by side with clinical notes

  • 12 Questions to Answer Before You Buy a Portable Travel Oxygen Concentrator → The pre-appointment guide from our RT team

  • How to Maintain Your Portable Oxygen Concentrator → Filters, batteries, sieve beds, and what to watch for

  • Shop Pulse Dose Concentrators → Inogen G4, G5, Rove 6, OxyGo NEXT, 3B Aer X, Rhythm P2-E7

  • Shop Continuous Flow Concentrators → OxLife Liberty 2, OxLife Independence, CAIRE Eclipse 5

You Deserve to Live Your Life — Not Watch It from the Sidelines

The right portable oxygen concentrators for sale isn’t just a piece of equipment. It’s your ticket back to the grandkids, the beach, the morning walks, and the trips you thought were behind you. Our Southwest Florida team is here to help you find exactly what you need — with no pressure, no guesswork, and clinical expertise you won’t find anywhere else.

Come in. Try it for 10 days. And breathe easy.

📞  Call 866-218-0902 to speak with a Respiratory Therapist today ✉  Email us: support@medicaldepartmentstore.com 📍  Walk in anytime at any of our five Southwest Florida locations

continous pulse

***$300 OFF IN STORE ONLY***

13 Products
13 Products
Continuous flow portable oxygen concentrators provide a steady, reliable oxygen supply for users who need consistent oxygen therapy at home or while traveling. Designed for comfort, safety, and ease of use, these units offer dependable performance with expert support and nationwide shipping.

Medical Department Store

Welcome to the Medical Department Store - Mobility Store. Join the Thousands of satisfied clients who have purchased their Mobility Scooters & Powerchairs at TheMedicalDepartmentStore.com.

Whatever your Mobility Needs, from small and portable to full-size and rugged, we have a Powerchair or Scooter that will fit the bill. The Medical Department Store offers all leading brands including Pride Mobility, Golden Technologies, and Merits.

Our expert staff can help you make your Scooter or Powerchair purchase with confidence. Purchase your Medical Products from the Medical Department Store.

We have a RESNA Certified, Seating Expert of Staff can help with your Seating and Mobility Needs!

Welcome to the Medical Department Store - Mobility Store. Join the Thousands of satisfied clients who have purchased their Mobility Scooters & Powerchairs at TheMedicalDepartmentStore.com.

Call Us at +1-866-218-0902 or one of our locations below!

Visit One of our 5 Locations

Sarasota

3672 Webber Street - Phone: 941-923-7556

Venice

1180 Jacaranda Blvd. - Phone: 941-497-2273

Naples

13030 Livingston Rd. - Phone: 239-529-2242

Port Charlotte

4265 Tamiami Trail - Phone: 941-743-6644

Fort Myers

8595 College Parkway - Phone: 239-482-6111

Hours: Monday- Friday 9AM-5PM | Saturday 9AM to 3PM

Logo 1
Logo 2
Logo 3
Logo 4
Logo 5