About Biofreeze

Biofreeze has been the standard in clinician-recommended topical pain relief for over 30 years — used in physical therapy clinics, chiropractic offices, athletic training rooms, and sports medicine practices worldwide. The formula is built around USP-grade menthol, which activates cold-sensitive nerve receptors to produce immediate cooling pain relief without the side effects of oral medications. Key botanical supporting ingredients — Ilex (an herbal extract from South America), Arnica, and Aloe — enhance the formula's comfort and skin care properties.

Biofreeze is non-systemic, meaning the active ingredients work locally at the application site without entering the bloodstream in meaningful amounts. It contains no NSAIDs, no salicylates, no parabens, no propylene glycol, and no addictive substances — making it appropriate for a wide range of patients including those who cannot take oral pain medications due to GI sensitivity, anticoagulant use, or personal preference.

Common Conditions Biofreeze Is Used For

• Sore muscles from exercise, overexertion, or prolonged activity
• Arthritis pain — osteoarthritis of the hands, knees, hips, and spine
• Back pain — muscular back pain, lumbar strain, upper back tension
• Neck pain and shoulder tension
• Joint pain — knees, elbows, wrists, ankles
• Post-workout muscle soreness and recovery
• Sprains, strains, and minor bruises
• Foot and plantar fascia discomfort
• Post-physical therapy or chiropractic session relief

Biofreeze Original Green vs. Colorless

Biofreeze is available in two color formulations — Original Green and Colorless. Both formulas deliver the same active menthol concentration and therapeutic effect. Original Green allows the user to see exactly where the product has been applied, which is useful in clinical settings where precise coverage documentation matters or for first-time users learning application technique. The Colorless formula eliminates any staining risk to clothing, sheets, or upholstery, making it the preferred choice for daily-use applications, use before dressing, and bedtime application. Choice between the two is entirely a matter of personal preference and use context.

Biofreeze for Clinics and Healthcare Facilities

Medical Department Store carries Biofreeze in clinic-sized quantities — 16 oz pumps, 32 oz pumps, and 1-gallon containers — for physical therapy clinics, chiropractic offices, athletic training rooms, and rehabilitation facilities that use Biofreeze as part of their patient treatment protocols. Bulk pricing and case quantities are available on select SKUs. Call our team for facility and bulk order inquiries: 1-866-218-0902  |  Mon–Fri 9am–5pm, Sat 9am–3pm EST.

Frequently Asked Questions

Can Biofreeze be used with other pain treatments?

Yes — Biofreeze is commonly used alongside physical therapy, chiropractic care, TENS/EMS therapy, and oral OTC pain medications without interaction concerns, as it is a topical product with no meaningful systemic absorption. It should not be applied over areas where other medicated patches or topicals are already in use, to broken or irritated skin, or in combination with heat therapy immediately after application.

Is Biofreeze FSA/HSA eligible?

Yes — Biofreeze products qualify for purchase using FSA (Flexible Spending Account) and HSA (Health Savings Account) funds as an OTC topical pain reliever.

What is the difference between the Biofreeze menthol patches and the Ultraflex Patch?

The standard Biofreeze Day & Night Patches use menthol as the active ingredient — the same mechanism as the roll-on, gel, and spray — providing a cooling pain relief effect for several hours. The Ultraflex Patch uses 4% lidocaine, a local anesthetic that works by blocking sodium channels in sensory nerve fibers to reduce pain signal transmission — a different mechanism entirely, not a cooling sensation but a numbing/blocking effect. Lidocaine patches are especially appropriate when sustained pain blocking is needed rather than a cooling sensation, and for users who prefer a non-menthol format. At 4%, the Ultraflex Patch delivers the maximum lidocaine concentration available over the counter.

Who should not use Biofreeze?

Individuals with known sensitivity or allergy to menthol, mint, or related compounds should not use Biofreeze menthol products. Biofreeze should not be used by children under 12 without physician guidance, on broken or rash-affected skin, near the eyes or mouth, or over other medicated topicals or patches. If skin irritation, burning, or rash develops, discontinue use and rinse with cool water. Pregnant or nursing individuals should consult their physician before use.

Questions about the Biofreeze product line, format selection, or bulk clinic orders? Our product specialists are here to help: 1-866-218-0902  |  Mon–Fri 9am–5pm, Sat 9am–3pm EST