HC325 Water Chamber for Fisher & Paykel HC100, HC105 and HC150 Humidifiers
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Fisher & Paykel Reusable CPAP Humidification Water Chamber
SKU: HC325S | For HC100 / HC150 / H150 Humidifiers | By Fisher & Paykel Healthcare
Genuine Replacement Chamber | 15.2 oz Capacity | Reusable & Washable | Fits HC100, HC150 & H150 Humidifiers | Restores Consistent Moisture Delivery | By Fisher & Paykel Healthcare
The genuine Fisher & Paykel reusable water chamber for the HC100, HC150, and H150 heated CPAP/BiPAP humidifiers. The water chamber is the removable tub inside the humidifier base that holds the water supply; the heater plate beneath it warms the water to deliver humidified air through the therapy circuit. Over time, mineral deposits from tap water accumulate on the chamber's interior surfaces, degrading heat transfer efficiency, compromising moisture output consistency, and making the chamber difficult to clean effectively. Hairline cracks or wear from repeated filling and washing can also develop, leading to leaks or inconsistent seal with the humidifier base. This genuine F&P replacement restores like-new moisture delivery performance at a known-fit with the HC150 base — eliminating leak risk and improper heating concerns associated with third-party substitute chambers. 15.2 oz capacity. Reusable and washable. By Fisher & Paykel Healthcare.
Specifications
| Specification | HC325S |
|---|---|
| SKU | HC325S |
| Chamber Type | Reusable (washable) |
| Water Capacity | 15.2 oz (approx. 450 mL) |
| Compatible Humidifiers | Fisher & Paykel HC100, HC150, H150 |
| Genuine OEM | Yes — genuine Fisher & Paykel Healthcare |
| Manufacturer | Fisher & Paykel Healthcare |
Note: also available as a disposable single-use chamber for single-patient clinical use. Contact us at 1-866-218-0902 for disposable chamber availability.
Key Features
- Genuine Fisher & Paykel replacement — OEM-specification chamber designed and manufactured by Fisher & Paykel Healthcare to exact-fit tolerances for the HC100, HC150, and H150 humidifier bases; eliminates the seal gaps, leak risk, and inconsistent heat transfer that can occur with third-party alternatives
- 15.2 oz water capacity — sized to supply sufficient water for most users' full overnight therapy sessions; capacity accommodates longer sessions, higher humidity settings, and warmer room environments where evaporation rate is higher
- Reusable and washable — designed for repeated use; can be washed regularly to remove mineral deposits and biological residue; more economical than disposable chambers for home care users who manage their own CPAP hygiene
- Restores consistent moisture delivery — a clean, undamaged chamber ensures proper contact with the heater plate and predictable heat transfer to the water; worn or mineral-coated chambers reduce heat efficiency and produce inconsistent humidity levels
- Perfect-fit for HC150 base — seats correctly in the heater plate tray and seals to the humidifier base without gaps; consistent seal prevents water leakage from the humidifier housing
- Replaces worn, cracked, or mineral-encrusted original chambers — extends the effective service life of the HC150 or HC100 humidifier without replacing the entire unit
Clinical FAQs
What is the difference between the reusable HC325 chamber and disposable chambers for the HC150?
The HC150 humidifier system is compatible with two chamber types: reusable chambers (such as the HC325) and disposable single-use chambers. The reusable HC325 chamber is made of durable materials designed to withstand repeated washing and long-term use in a home care setting — it is the standard option for personal home CPAP users who clean their equipment on a routine schedule. Disposable chambers are designed for single-patient or limited-use clinical settings — hospitals, sleep labs, or post-surgical recovery environments where hygienic isolation between patients is required and the chamber is discarded after use rather than being cleaned and reused. For home care users with an established CPAP hygiene routine, the reusable HC325 is the practical and economical choice; a single reusable chamber, properly cleaned, typically provides several months of service before replacement is needed. For clinical facility settings where multiple patients use HC150 humidifiers in sequence, disposable chambers eliminate the cross-contamination risk of a reusable chamber and the labor of chamber sanitization between patients. Contact us to discuss disposable chamber availability for clinical settings.
How often should the HC150 water chamber be cleaned and when should it be replaced?
Fisher & Paykel and standard CPAP hygiene guidelines recommend cleaning the humidifier water chamber daily — empty any remaining water, rinse the chamber with warm water, and allow it to air dry before the next use. A more thorough wash with mild dish soap and warm water should be performed at least once per week, with thorough rinsing to remove all soap residue before use. Distilled water is strongly recommended over tap water for filling the chamber — distilled water contains no dissolved minerals, which eliminates the primary source of mineral deposit buildup on the chamber's interior surfaces. The chamber should be replaced when: visible mineral deposits cannot be removed with regular cleaning; hairline cracks appear in the plastic; the chamber no longer seats flush and level in the humidifier base; a persistent musty or unusual odor remains after cleaning; or the chamber is more than 6 to 12 months old and showing visible wear. Many CPAP supply providers and insurance plans recommend annual replacement of the humidifier water chamber as part of a routine CPAP supply replenishment schedule. Call us at 1-866-218-0902 to discuss your CPAP supply replenishment needs.
How does the humidifier chamber affect CPAP therapy comfort and compliance?
The humidifier water chamber is the source of all moisture in heated CPAP humidification — without it, the HC150's Ambient Tracking and heater plate technology have no water to heat. A degraded, mineral-coated, or cracked chamber directly affects therapy quality in several ways. Mineral deposits on the interior surfaces and on the bottom of the chamber reduce thermal contact between the water and the heater plate, lowering the effective heating efficiency and reducing the moisture output to the patient. Inconsistent moisture output results in variable humidity levels throughout the night — the patient may receive too little humidification in the early portion of a session (when the deposit-impaired heating is at its worst) and more toward the end as the water temperature eventually builds. For CPAP therapy users, consistent humidity throughout the night matters: too little humidity allows the nasal mucosa to dry, causing congestion, nasal irritation, and airway discomfort that wakes the patient or reduces the quality of sleep during therapy. Approximately 80% of CPAP users report nasal or upper airway dryness as a complaint — maintaining a clean, functional humidifier chamber in good condition is one of the most direct actions a CPAP user can take to prevent this discomfort and protect their long-term therapy compliance.
Questions about the HC325 chamber, HC150 humidifier supplies, or CPAP equipment? Call our product specialists: 1-866-218-0902 | Mon–Fri 9am–5pm, Sat 9am–3pm EST

