McKesson 5-Liter Compact Concentrator with Oxygen Sensing Device
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The McKesson 5-Liter Compact Concentrator with Oxygen Sensing Device (146-525DS) is a reliable, compact 5 LPM home oxygen concentrator built on the proven DeVilbiss 525DS platform — 34% more compact than traditional 5-liter concentrators, making it noticeably easier to position in smaller rooms, beside a bed, or anywhere space is limited. At 36 lbs with smooth-rolling casters and top and side handles, it moves easily between rooms for patients who use oxygen throughout the day.
The 146-525DS includes an exclusive Oxygen Sensing Device (OSD) as standard — continuously monitoring oxygen purity output to ensure reliable, accurate delivery and alerting the user if levels fall outside safe parameters. Turn-Down Technology automatically reduces system pressure at lower flow settings, cutting stress on compressor bearings and internal fittings by up to 35% and reducing power consumption — extending component life and lowering electricity costs over time. The recessed humidifier nook protects connections from accidental damage. Operates at 48 dBA for quiet home use. HCPCS code E1390.
5 LPM continuous flow · 36 lbs · 48 dBA · 87%–96% O2 · OSD oxygen sensing · Turn-Down Technology · Compact design · HCPCS E1390 · Flame-retardant cabinet. Prescription required before shipment.
34% More Compact. OSD Standard. Turn-Down Technology.
Full Specifications
| Model | McKesson 146-525DS |
| Flow Rate | 0.5 to 5.0 LPM continuous flow |
| Oxygen Concentration | 87% to 96% |
| Oxygen Sensing | OSD — continuous purity monitoring standard |
| Noise Level | 48 dBA |
| Weight | 36 lbs |
| Dimensions | 24.5"H x 13.5"W x 12"D |
| Compact Design | 34% smaller than traditional 5-liter units |
| Technology | Turn-Down Technology — reduces system pressure at lower flow settings |
| Humidifier | Recessed humidifier nook |
| Cabinet | Flame-retardant |
| Plug Type | 2-prong |
| Pressure Relief Valve | Yes |
| HCPCS Code | E1390 |
| Latex Free | Yes — not made with natural rubber latex |
| Warranty | Limited warranty |
| Prescription Required | Yes — required before shipment |
Frequently Asked Questions
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Need Oxygen Away From Home Too?
The McKesson 5-Liter is designed for stationary home use and requires a wall outlet. If you also need oxygen therapy during errands, appointments, or travel, a portable oxygen concentrator is the right complement. We carry a full range of battery-powered portable concentrators — including FAA-approved models for air travel.
Browse Portable Oxygen Concentrators →
Nationwide Shipping & Local SW Florida Support
Medical Department Store ships home oxygen concentrators nationwide to residential addresses and healthcare facilities across all 50 states. Local in-person support is available at all five of our Southwest Florida locations — Venice, Sarasota, Port Charlotte, Fort Myers, and Naples. Our respiratory specialists are available before and after purchase to answer questions, assist with prescription submission, and help you get the most from your equipment.
📞 866-218-0902 · Mon–Fri 9AM–5PM · Sat 9AM–3PM · Find your nearest location →

